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human CAPG shRNA silencing Adenovirus

Name 
Ad-h-CAPG-shRNA
Cat No 
shADV-204034
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CAPG.

shADV-204034
Ad-h-CAPG-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CAPG (capping actin protein, gelsolin like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Actin regulatory protein CAP-G; actin-regulatory protein CAP-G; AFCP; capping protein (actin filament), gelsolin-like; epididymis secretory protein Li 66; gelsolin-like capping protein; HEL-S-66; macrophage-capping protein; MCP
Description (eCommerce)
CAPG is a member of the gelsolin/villin family of actin-regulatory proteins. CAPG reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cell [taken from NCBI Entrez Gene (Gene ID: 822)].
Description (Vector)
CAPG encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene.
Gene ID
822
Gene Name (eCommerce)
capping actin protein, gelsolin like
Gene Name (Vector)
capping actin protein, gelsolin like
Gene Symbol
CAPG
HGNC ID
HGNC:1474
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1047
ORF Size (bp)
1047 bp
Protein Name (eCommerce)
Macrophage-capping protein
RefSeq ID
NM_001747
RefSeq Synonyms
NM_001747, NM_001320734, NM_001320733, NM_001320732, NM_001256140, NM_001256139, BC014549, BC000728,
Research Areas
Immunology
Research Areas (Faceted)
immunology
Species
human
Target Sentence
CAPG is a member of the gelsolin/villin family of actin-regulatory proteins. CAPG reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cell [taken from NCBI Entrez Gene (Gene ID: 822)].
UniGene ID
Hs.516155
UniProt ID (eCommerce)
P40121

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.