human CAP1 shRNA silencing Adenovirus

Name 
Ad-h-CAP1-shRNA
Cat No 
shADV-204031
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CAP1.

shADV-204031
Ad-h-CAP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CAP1 (adenylate cyclase associated protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
adenylate cyclase associated protein 1; adenylyl cyclase-associated protein 1; CAP; CAP 1; CAP, adenylate cyclase-associated protein 1; CAP1-PEN; testis secretory sperm-binding protein Li 218p
Description (eCommerce)
Adenylyl cyclase-associated protein 1 (CAP1) directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q01518].
Description (Vector)
CAP1 is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. The human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. Alternatively spliced transcript variants have been identified.
Gene ID
10487
Gene Name (eCommerce)
cyclase associated actin cytoskeleton regulatory protein 1
Gene Name (Vector)
adenylate cyclase associated protein 1
Gene Symbol
CAP1
HGNC ID
HGNC:20040
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1428
ORF Size (bp)
1428 bp
Protein Name (eCommerce)
Adenylyl cyclase-associated protein 1
RefSeq ID
NM_006367
RefSeq Synonyms
NM_006367, NM_001330502, NM_001105530, BC095440, BC013963,
Research Areas
Axon Guidance,Cytoskeleton,Immunology,Insulin Signaling,Neurobiology,Signal Transduction
Research Areas (Faceted)
cell_biology,immunology,neurobiology,signal_transduction
Species
human
Target Sentence
Adenylyl cyclase-associated protein 1 (CAP1) directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q01518].
UniGene ID
Hs.713078
UniProt ID (eCommerce)
Q01518

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.