human CANX shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CANX.
shADV-204029
Ad-h-CANX-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CANX (calnexin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
calnexin; CNX; epididymis secretory sperm binding protein; IP90; major histocompatibility complex class I antigen-binding protein p88; P90
Description (eCommerce)
Calnexin is a molecular chaperone. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. Calnexin may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation [taken from NCBI Entrez Gene (Gene ID: 821)].
Description (Vector)
CANX encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.
Gene ID
821
Gene Name (eCommerce)
calnexin
Gene Name (Vector)
calnexin
Gene Symbol
CANX
HGNC ID
HGNC:1473
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1779
ORF Size (bp)
1779 bp
Protein Name (eCommerce)
Calnexin
RefSeq ID
NM_001746
RefSeq Synonyms
NM_001746, NM_001024649, BC042843, BC003552,
Research Areas
Aging,Antigen Processing and Presentation,Host-Virus Interactions,Immunology,Metabolism/Metabolic Process,Neurobiology,Protein Folding,Signal Transduction,Translational Control,TSH Signaling
Research Areas (Faceted)
cell_biology,immunology,infectious_disease,metabolism,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
Calnexin is a molecular chaperone. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. Calnexin may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation [taken from NCBI Entrez Gene (Gene ID: 821)].
UniGene ID
Hs.699155
UniProt ID (eCommerce)
P27824
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.