human CACNA2D2 shRNA silencing Adenovirus

Name 
Ad-h-CACNA2D2-shRNA
Cat No 
shADV-203907
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CACNA2D2.

shADV-203907
Ad-h-CACNA2D2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CACNA2D2 (calcium voltage-gated channel auxiliary subunit alpha2delta 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CACNA2D
Description (Vector)
CACNA2D2 encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.
Gene ID
9254
Gene Name (Vector)
calcium voltage-gated channel auxiliary subunit alpha2delta 2
Gene Symbol
CACNA2D2
HGNC ID
HGNC:1400
ORF Size (aa)
3438
ORF Size (bp)
3438 bp
RefSeq ID
NM_006030
RefSeq Synonyms
NM_006030, NM_001291101, NM_001174051, NM_001005505, BC152438,
Species
human
UniGene ID
Hs.674666

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.