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human CA4 shRNA silencing Adenovirus

Name 
Ad-h-CA4-shRNA
Cat No 
shADV-203875
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CA4.

shADV-203875
Ad-h-CA4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CA4 (carbonic anhydrase 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CAIV; Car4; RP17
Description (Vector)
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known; however, it may have a role in inherited renal abnormalities of bicarbonate transport.
Gene ID
762
Gene Name (Vector)
carbonic anhydrase 4
Gene Symbol
CA4
HGNC ID
HGNC:1375
ORF Size (aa)
939
ORF Size (bp)
939 bp
RefSeq ID
NM_000717
RefSeq Synonyms
NM_000717, BC074768, BC069649, BC057792,
Species
human
UniGene ID
Hs.89485

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.