human C16ORF38 shRNA silencing Adenovirus

Name
Ad-h-C16ORF38-shRNA

Cat No
shADV-202732

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human PTX4.

shADV-202732

Ad-h-C16ORF38-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PTX4 (pentraxin 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

C16orf38

Description (Vector)

PTX4 belongs to the pentraxin (PTX) superfamily of multifunctional conserved proteins. Pentraxins are characterized by a cyclic multimeric structure and a conserved C-terminal pentraxin domain of approximately 200 amino acids. All pentraxins have a conserved 8-amino acid sequence, HxCxS/TWxS, in which x is any amino acid, within their pentraxin domain. Pentraxins are divided into short proteins, such as C-reactive protein (CRP; MIM 123260) and serum amyloid P protein (APCS; MIM 104770), and long proteins, such as PTX3 (MIM 602492) and PTX4. Some PTXs are part of the humoral arm of innate immunity and behave as functional ancestors of antibodies by mediating agglutination, complement activation, and opsonization (summary by Martinez de la Torre et al., 2010 (PubMed 20357257)).(supplied by OMIM, Jun 2010)

Gene ID

390667

Gene Name (Vector)

pentraxin 4

Gene Symbol

PTX4

HGNC ID

HGNC:14171

ORF Size (aa)

1419

ORF Size (bp)

1419 bp

RefSeq ID

NM_001013658

RefSeq Synonyms

NM_001328608, NM_001013658, BC156944, BC156066,

Species

human

UniGene ID

Hs.553770

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.