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human BMP2K shRNA silencing Adenovirus

Name 
Ad-h-BMP2K-shRNA
Cat No 
shADV-202192
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human BMP2K.

shADV-202192
Ad-h-BMP2K-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human BMP2K (BMP2 inducible kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BIKE; HRIHFB2017
Description (Vector)
BMP2K is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
55589
Gene Name (Vector)
BMP2 inducible kinase
Gene Symbol
BMP2K
HGNC ID
HGNC:18041
ORF Size (aa)
1989
ORF Size (bp)
1989 bp
RefSeq ID
NM_017593
RefSeq Synonyms
NM_198892, NM_017593, BC036021,
Species
human
UniGene ID
Hs.146551

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.