human BAG1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human BAG1.
shADV-201934
Ad-h-BAG1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human BAG1 (BCL2 associated athanogene 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BAG-1; HAP; RAP46
Description (Vector)
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
Gene ID
573
Gene Name (Vector)
BCL2 associated athanogene 1
Gene Symbol
BAG1
HGNC ID
HGNC:937
ORF Size (aa)
1038
RefSeq ID
NM_004323
RefSeq Synonyms
NM_004323, NM_001172415, BC014774, BC001936,
Species
human
UniGene ID
Hs.377484
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.