human B3GALT1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human B3GALT1.
shADV-201873
Ad-h-B3GALT1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human B3GALT1 (beta-1,3-galactosyltransferase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
beta3Gal-T1
Description (Vector)
B3GALT1 is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). B3GALT1 is expressed exclusively in the brain. The encoded protein shows strict donor substrate specificity for UDP-galactose.
Gene ID
8708
Gene Name (Vector)
beta-1,3-galactosyltransferase 1
Gene Symbol
B3GALT1
HGNC ID
HGNC:916
ORF Size (aa)
981
ORF Size (bp)
981 bp
RefSeq ID
NM_020981
RefSeq Synonyms
NM_020981, BC104813, BC101545,
Species
human
UniGene ID
Hs.657258
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.