human AZU1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human AZU1.
shADV-201865
Ad-h-AZU1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human AZU1 (azurocidin 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AZAMP; AZU; CAP37; HBP; hHBP; HUMAZUR; NAZC
Description (Vector)
Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. The protein encoded by this gene is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.
Gene ID
566
Gene Name (Vector)
azurocidin 1
Gene Symbol
AZU1
HGNC ID
HGNC:913
ORF Size (aa)
756
ORF Size (bp)
756 bp
RefSeq ID
NM_001700
RefSeq Synonyms
NM_001700, BC093933, BC093931, BC069495,
Species
human
UniGene ID
Hs.72885
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.
