human ATP5O shRNA silencing Adenovirus

Name 
Ad-h-ATP5O-shRNA
Cat No 
shADV-201734
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ATP5O.

shADV-201734
Ad-h-ATP5O-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ATP5O (ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ATP synthase peripheral stalk subunit OSCP; ATP synthase subunit O, mitochondrial; ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit; ATP5O; ATPO; HMC08D05; human ATP synthase OSCP subunit; Oligomycin sensitivity conferral protein; oligomycin sensitivity conferral protein oscp-like protein; oligomycin sensitivity conferring protein; OSCP
Description (eCommerce)
ATP5O is a component of the F-type ATPase found in the mitochondrial matrix. F-type ATPases are composed of a catalytic core and a membrane proton channel. ATP5O appears to be part of the connector linking these two components and may be involved in transmission of conformational changes or proton conductance [taken from NCBI Entrez Gene (Gene ID: 539)].
Description (Vector)
ATP5O is a component of the F-type ATPase found in the mitochondrial matrix. F-type ATPases are composed of a catalytic core and a membrane proton channel. The encoded protein appears to be part of the connector linking these two components and may be involved in transmission of conformational changes or proton conductance.
Gene ID
539
Gene Name (eCommerce)
ATP synthase peripheral stalk subunit OSCP
Gene Name (Vector)
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
Gene Symbol
ATP5O
HGNC ID
HGNC:850
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
642
ORF Size (bp)
642 bp
Protein Name (eCommerce)
ATP synthase subunit O, mitochondrial
RefSeq ID
NM_001697
RefSeq Synonyms
NM_001697, BC022865, BC021233,
Research Areas
Alzheimer's Disease,Cell Biology,Huntington's Disease,Metabolism/Metabolic Process,Mitochondrion,Neurobiology,Neurodegeneration,Parkinson's Disease,Transport
Research Areas (Faceted)
neurobiology,cell_biology,metabolism
Species
human
Target Sentence
ATP5O is a component of the F-type ATPase found in the mitochondrial matrix. F-type ATPases are composed of a catalytic core and a membrane proton channel. ATP5O appears to be part of the connector linking these two components and may be involved in transmission of conformational changes or proton conductance [taken from NCBI Entrez Gene (Gene ID: 539)].
UniGene ID
Hs.409140
UniProt ID (eCommerce)
P48047

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.