human ATG4A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ATG4A.
shADV-201640
Ad-h-ATG4A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ATG4A (autophagy related 4A cysteine peptidase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
APG4A; AUTL2
Description (Vector)
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.
Gene ID
115201
Gene Name (Vector)
autophagy related 4A cysteine peptidase
Gene Symbol
ATG4A
HGNC ID
HGNC:16489
ORF Size (aa)
1197
ORF Size (bp)
1197 bp
RefSeq ID
NM_052936
RefSeq Synonyms
NM_178271, NM_178270, NM_052936, NM_001321290, NM_001321289, NM_001321288, NM_001321287, BC061696, BC041862,
Species
human
UniGene ID
Hs.8763
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.