human ASH2L shRNA silencing Adenovirus

Name 
Ad-h-ASH2L-shRNA
Cat No 
shADV-201556
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human ASH2L.

shADV-201556
Ad-h-ASH2L-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ASH2L (ASH2 like histone lysine methyltransferase complex subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ASH2; ash2 (absent, small, or homeotic)-like; ASH2L1; ASH2L2; ASH2-like protein; Bre2; set1/Ash2 histone methyltransferase complex subunit ASH2
Description (eCommerce)
ASH2 (absent, small, or homeotic discs 2) is a subunit of a human Set1-like histone methyltransferase (HMT) complex. The Set-1 like complexes are responsible for mono-, di-, and tri-methylation of histone H3 K4. ASH2 associates with a multitude of proteins in a number of Set1-like complexes which include various combinations of MLL, MLL2, MLL3, MLL4, RBBP5,WDR5, hDPY-30, hSwd2, CXXC1, HCF1, Menin, PTIP, PA1, NCOA6, and UTX.
Gene ID
9070
Gene Name (eCommerce)
ASH2 like, histone lysine methyltransferase complex subunit
Gene Name (Vector)
ASH2 like histone lysine methyltransferase complex subunit
Gene Symbol
ASH2L
HGNC ID
HGNC:744
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1605
ORF Size (bp)
1605 bp
Protein Name (eCommerce)
Set1/Ash2 histone methyltransferase complex subunit ASH2
RefSeq ID
NM_004674
RefSeq Synonyms
NM_004674, NM_001282272, NM_001261832, NM_001105214, BC015936,
Research Areas
DNA Damage/Repair,Estrogen Signaling,Histone Modification,Immunology,Neurobiology,Signal Transduction,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
signal_transduction,genetics,transcription_translation,signal_transduction,immunology,neurobiology,genetics,transcription_translation,cell_biology
Species
human
Target Sentence
ASH2 (absent, small, or homeotic discs 2) is a subunit of a human Set1-like histone methyltransferase (HMT) complex. The Set-1 like complexes are responsible for mono-, di-, and tri-methylation of histone H3 K4. ASH2 associates with a multitude of proteins in a number of Set1-like complexes which include various combinations of MLL, MLL2, MLL3, MLL4, RBBP5,WDR5, hDPY-30, hSwd2, CXXC1, HCF1, Menin, PTIP, PA1, NCOA6, and UTX.
UniGene ID
Hs.521530
UniProt ID (eCommerce)
Q9UBL3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.