human ASB7 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ASB7.
shADV-201535
Ad-h-ASB7-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ASB7 (ankyrin repeat and SOCS box containing 7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
ASB7 belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described.
Gene ID
140460
Gene Name (Vector)
ankyrin repeat and SOCS box containing 7
Gene Symbol
ASB7
HGNC ID
HGNC:17182
ORF Size (aa)
825
ORF Size (bp)
825 bp
RefSeq ID
NM_024708
RefSeq Synonyms
NM_198243, NM_024708, BC063581,
Species
human
UniGene ID
Hs.709044
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.