human ARSB shRNA silencing Adenovirus

Name 
Ad-h-ARSB-shRNA
Cat No 
shADV-201485
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human ARSB.

shADV-201485
Ad-h-ARSB-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ARSB (arylsulfatase B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ASB; G4S; MPS6
Description (Vector)
Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Gene ID
411
Gene Name (Vector)
arylsulfatase B
Gene Symbol
ARSB
HGNC ID
HGNC:714
ORF Size (aa)
1242
ORF Size (bp)
1242 bp
RefSeq ID
NM_000046
RefSeq Synonyms
NM_198709, NM_000046, BC029051,
Species
human
UniGene ID
Hs.604199

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.