human ARPC2 shRNA silencing Adenovirus

Name 
Ad-h-ARPC2-shRNA
Cat No 
shADV-201463
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ARPC2.

shADV-201463
Ad-h-ARPC2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ARPC2 (actin related protein 2/3 complex subunit 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
actin related protein 2/3 complex, subunit 2, 34kDa; actin-related protein 2/3 complex subunit 2; ARC34; arp2/3 complex 34 kDa subunit; ARP2/3 protein complex subunit 34; p34-Arc; PNAS-139; PRO2446; testis tissue sperm-binding protein Li 53e
Description (eCommerce)
(ARPC2) is one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined [taken from NCBI Entrez Gene (Gene ID: 10109)].
Description (Vector)
ARPC2 encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined.
Gene ID
10109
Gene Name (eCommerce)
actin related protein 2/3 complex subunit 2
Gene Name (Vector)
actin related protein 2/3 complex subunit 2
Gene Symbol
ARPC2
HGNC ID
HGNC:705
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
903
ORF Size (bp)
903 bp
Protein Name (eCommerce)
Actin-related protein 2/3 complex subunit 2
RefSeq ID
NM_005731
RefSeq Synonyms
NM_152862, NM_005731, BC000590,
Research Areas
Cytoskeleton,Golgi Apparatus,Immunology,Innate Immunity,Neurobiology,PDGF Signaling,RAC1 Signaling,Signal Transduction,Synapse
Research Areas (Faceted)
cell_biology,immunology,neurobiology,signal_transduction
Species
human
Target Sentence
(ARPC2) is one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined [taken from NCBI Entrez Gene (Gene ID: 10109)].
UniGene ID
Hs.529303
UniProt ID (eCommerce)
O15144

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.