human ARHGEF7 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ARHGEF7.
shADV-201374
Ad-h-ARHGEF7-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ARHGEF7 (Rho guanine nucleotide exchange factor 7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BETA-PIX; COOL-1; COOL1; Nbla10314; P50; P50BP; P85; P85COOL1; P85SPR; PAK3; PIXB
Description (Vector)
Rho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. This protein can induce membrane ruffling. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene ID
8874
Gene Name (Vector)
Rho guanine nucleotide exchange factor 7
Gene Symbol
ARHGEF7
HGNC ID
HGNC:15607
ORF Size (aa)
2262
ORF Size (bp)
2262 bp
RefSeq ID
NM_003899
RefSeq Synonyms
NM_145735, NM_003899, NM_001330598, NM_001330597, NM_001320854, NM_001320853, NM_001320852, NM_001320851, NM_001113513, NM_001113512, NM_001113511, BC060776, BC033905,
Species
human
UniGene ID
Hs.508738
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.