human ANXA7 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ANXA7.
shADV-201063
Ad-h-ANXA7-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ANXA7 (annexin A7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ANX7; SNX; SYNEXIN
Description (Vector)
Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.
Gene ID
310
Gene Name (Vector)
annexin A7
Gene Symbol
ANXA7
HGNC ID
HGNC:545
ORF Size (aa)
1401
ORF Size (bp)
1401 bp
RefSeq ID
NM_001156
RefSeq Synonyms
NM_004034, NM_001320880, NM_001320879, NM_001156, BC002632,
Species
human
UniGene ID
Hs.705617
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.