human ANO6 shRNA silencing Adenovirus

Name
Ad-h-ANO6-shRNA

Cat No
shADV-201022

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human ANO6.

shADV-201022

Ad-h-ANO6-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ANO6 (anoctamin 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

BDPLT7; SCTS; TMEM16F

Description (Vector)

ANO6 encodes a multi-pass transmembrane protein that belongs to the anoctamin family. This protein is an essential component for the calcium-dependent exposure of phosphatidylserine on the cell surface. The scrambling of phospholipid occurs in various biological systems, such as when blood platelets are activated, they expose phosphatidylserine to trigger the clotting system. Mutations in this gene are associated with Scott syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene ID

196527

Gene Name (Vector)

anoctamin 6

Gene Symbol

ANO6

HGNC ID

HGNC:25240

ORF Size (aa)

2796

ORF Size (bp)

2796 bp

RefSeq ID

NM_001025356

RefSeq Synonyms

NM_001204803, NM_001142680, NM_001142679, NM_001142678, NM_001025356, BC136445, BC098410,

Species

human

UniGene ID

Hs.696326

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.