human ALDH4A1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ALDH4A1.
shADV-200741
Ad-h-ALDH4A1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ALDH4A1 (aldehyde dehydrogenase 4 family member A1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ALDH4; P5CD; P5CDh
Description (Vector)
This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Gene ID
8659
Gene Name (Vector)
aldehyde dehydrogenase 4 family member A1
Gene Symbol
ALDH4A1
HGNC ID
HGNC:406
ORF Size (aa)
1692
ORF Size (bp)
1692 bp
RefSeq ID
NM_170726
RefSeq Synonyms
NM_170726, NM_003748, NM_001319218, NM_001161504, BC023600, BC007581,
Species
human
UniGene ID
Hs.77448
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.