human ALAS2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ALAS2.
shADV-200714
Ad-h-ALAS2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ALAS2 (5′-aminolevulinate synthase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ALAS-E; ALASE; ANH1; ASB; SIDBA1; XLDPP; XLEPP; XLSA
Description (Vector)
The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
212
Gene Name (Vector)
5'-aminolevulinate synthase 2
Gene Symbol
ALAS2
HGNC ID
HGNC:397
ORF Size (aa)
1725
ORF Size (bp)
1725 bp
RefSeq ID
NM_000032
RefSeq Synonyms
NM_001037968, NM_001037967, NM_000032, BC030230,
Species
human
UniGene ID
Hs.555936
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.