human AKR7A2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human AKR7A2.
shADV-200694
Ad-h-AKR7A2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human AKR7A2 (aldo-keto reductase family 7 member A2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AFAR; AFAR1; AFB1-AR1; AKR7
Description (Vector)
AKR7A2 belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde.
Gene ID
8574
Gene Name (Vector)
aldo-keto reductase family 7 member A2
Gene Symbol
AKR7A2
HGNC ID
HGNC:389
ORF Size (aa)
993
ORF Size (bp)
993 bp
RefSeq ID
NM_003689
RefSeq Synonyms
NM_003689, NM_001320979, BC013996, BC012171, BC011586, BC010852, BC004111,
Species
human
UniGene ID
Hs.571886
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.