human AK1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human AK1.
shADV-200634
Ad-h-AK1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human AK1 (adenylate kinase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HTL-S-58j
Description (Vector)
Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.
Gene ID
203
Gene Name (Vector)
adenylate kinase 1
Gene Symbol
AK1
HGNC ID
HGNC:361
ORF Size (aa)
585
ORF Size (bp)
585 bp
RefSeq ID
NM_000476
RefSeq Synonyms
NM_001318122, NM_001318121, NM_000476, BC100022, BC001116,
Species
human
UniGene ID
Hs.175473
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.