human AGL shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human AGL.
shADV-200561
Ad-h-AGL-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human AGL (amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GDE
Description (Vector)
AGL encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described.
Gene ID
178
Gene Name (Vector)
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
Gene Symbol
AGL
HGNC ID
HGNC:321
ORF Size (aa)
4599
ORF Size (bp)
4599 bp
RefSeq ID
NM_000028
RefSeq Synonyms
NM_000646, NM_000645, NM_000644, NM_000643, NM_000642, NM_000028, BC078663,
Species
human
UniGene ID
Hs.904
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.