human ADRM1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ADRM1.
shADV-200513
Ad-h-ADRM1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ADRM1 (adhesion regulating molecule 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
110 kDa cell membrane glycoprotein; Adhesion-regulating molecule 1; ARM1; ARM-1; GP110; hRpn13; M(r) 110,000 surface antigen; proteasomal ubiquitin receptor ADRM1; proteasome regulatory particle non-ATPase 13; rpn13 homolog
Description (eCommerce)
Adhesion-regulating molecule 1 (ADRM1) functions as a proteasomal ubiquitin receptor. It has been shown to recruit the deubiquitinating enzyme UCHL5 at the 26S proteasome and promote its activity. ADRM1 is homologous to the Rpn13 subunit of the 19S complex in yeast [Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q16186].
Description (Vector)
ADRM1 is an integral plasma membrane protein which promotes cell adhesion. The encoded protein is thought to undergo O-linked glycosylation. Expression of this gene has been shown to be induced by gamma interferon in some cancer cells. Two transcript variants encoding the same protein have been found for this gene.
Gene ID
11047
Gene Name (eCommerce)
adhesion regulating molecule 1
Gene Name (Vector)
adhesion regulating molecule 1
Gene Symbol
ADRM1
HGNC ID
HGNC:15759
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1224
ORF Size (bp)
1224 bp
Protein Name (eCommerce)
Proteasomal ubiquitin receptor ADRM1
RefSeq ID
NM_007002
RefSeq Synonyms
NM_175573, NM_007002, NM_001281438, NM_001281437, BC017245,
Research Areas
Complexome,Proteasome,Transcription Factor/Regulator,Ubiquitination
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Adhesion-regulating molecule 1 (ADRM1) functions as a proteasomal ubiquitin receptor. It has been shown to recruit the deubiquitinating enzyme UCHL5 at the 26S proteasome and promote its activity. ADRM1 is homologous to the Rpn13 subunit of the 19S complex in yeast [Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q16186].
UniGene ID
Hs.90107
UniProt ID (eCommerce)
Q16186
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.