human ADAMTSL2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ADAMTSL2.
shADV-200397
Ad-h-ADAMTSL2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ADAMTSL2 (ADAMTS like 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GPHYSD1
Description (Vector)
ADAMTSL2 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia.
Gene ID
9719
Gene Name (Vector)
ADAMTS like 2
Gene Symbol
ADAMTSL2
HGNC ID
HGNC:14631
ORF Size (aa)
2856
ORF Size (bp)
2856 bp
RefSeq ID
NM_014694
RefSeq Synonyms
NM_014694, NM_001145320, BC050544,
Species
human
UniGene ID
Hs.522543
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.