human ADAMTS18 shRNA silencing Adenovirus

Name 
Ad-h-ADAMTS18-shRNA
Cat No 
shADV-200384
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ADAMTS18.

shADV-200384
Ad-h-ADAMTS18-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ADAMTS18 (ADAM metallopeptidase with thrombospondin type 1 motif 18). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ADAMTS21; KNO2; MMCAT
Description (Vector)
ADAMTS18 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.
Gene ID
170692
Gene Name (Vector)
ADAM metallopeptidase with thrombospondin type 1 motif 18
Gene Symbol
ADAMTS18
HGNC ID
HGNC:17110
ORF Size (aa)
3666
ORF Size (bp)
3666 bp
RefSeq ID
NM_199355
RefSeq Synonyms
NM_199355, NM_001326358, BC063283,
Species
human
UniGene ID
Hs.188746

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.