human ACTL6B shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ACTL6B.
shADV-200295
Ad-h-ACTL6B-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ACTL6B (actin like 6B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ACTL6; arpNalpha; BAF53B
Description (Vector)
ACTL6B is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain.
Gene ID
51412
Gene Name (Vector)
actin like 6B
Gene Symbol
ACTL6B
HGNC ID
HGNC:160
ORF Size (aa)
1281
ORF Size (bp)
1281 bp
RefSeq ID
NM_016188
RefSeq Synonyms
NM_016188, BC020944,
Species
human
UniGene ID
Hs.259831
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.