human ACSS2 shRNA silencing Adenovirus

Name 
Ad-h-ACSS2-shRNA
Cat No 
shADV-200264
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ACSS2.

shADV-200264
Ad-h-ACSS2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ACSS2 (acyl-CoA synthetase short-chain family member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
96
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ACAS2; ACECS; acetate thiokinase; acetate-CoA ligase; Acetate--CoA ligase; Acetyl-CoA synthetase; acetyl-Coenzyme A synthetase 2 (ADP forming); acetyl-coenzyme A synthetase, cytoplasmic; ACS; ACSA; acyl-activating enzyme; Acyl-CoA synthetase short-chain family member 2; cytoplasmic acetyl-coenzyme A synthetase; dJ1161H23.1
Description (eCommerce)
Acetyl-coenzyme A synthetase (ACSS2) is a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. ACSS2 acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP [taken from NCBI Entrez Gene (Gene ID: 55902)].
Description (Vector)
ACSS2 encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants.
Gene ID
55902
Gene Name (eCommerce)
acyl-CoA synthetase short chain family member 2
Gene Name (Vector)
acyl-CoA synthetase short-chain family member 2
Gene Symbol
ACSS2
HGNC ID
HGNC:15814
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2106
ORF Size (bp)
2106 bp
Protein Name (eCommerce)
Acetyl-coenzyme A synthetase, cytoplasmic
RefSeq ID
NM_018677
RefSeq Synonyms
NM_018677, NM_001242393, NM_001076552, BC098422, BC012172, BC010141,
Research Areas
Metabolism/Metabolic Process
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
Acetyl-coenzyme A synthetase (ACSS2) is a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. ACSS2 acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP [taken from NCBI Entrez Gene (Gene ID: 55902)].
UniGene ID
Hs.517034
UniProt ID (eCommerce)
Q9NR19

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.