human ABCD1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ABCD1.
shADV-200084
Ad-h-ABCD1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ABCD1 (ATP binding cassette subfamily D member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ABC42; ALD; ALDP; AMN
Description (Vector)
ABCD1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.
Gene ID
215
Gene Name (Vector)
ATP binding cassette subfamily D member 1
Gene Symbol
ABCD1
HGNC ID
HGNC:61
ORF Size (aa)
2238
ORF Size (bp)
2238 bp
RefSeq ID
NM_000033
RefSeq Synonyms
NM_000033, BC025358, BC015541,
Species
human
UniGene ID
Hs.159546
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.