human ABCB6 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ABCB6.
shADV-200061
Ad-h-ABCB6-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ABCB6 (ATP binding cassette subfamily B member 6 (Langereis blood group)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ABC; ABC14; DUH3; LAN; MCOPCB7; MTABC3; PRP; PSHK2; umat
Description (Vector)
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
Gene ID
10058
Gene Name (Vector)
ATP binding cassette subfamily B member 6 (Langereis blood group)
Gene Symbol
ABCB6
HGNC ID
HGNC:47
ORF Size (aa)
2529
ORF Size (bp)
2529 bp
RefSeq ID
NM_005689
RefSeq Synonyms
NM_005689, BC000559,
Species
human
UniGene ID
Hs.107911
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.