human A2M shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human A2M.
shADV-200006
Ad-h-A2M-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human A2M (alpha-2-macroglobulin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
A2MD; CPAMD5; FWP007; S863-7
Description (Vector)
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
Gene ID
2
Gene Name (Vector)
alpha-2-macroglobulin
Gene Symbol
A2M
HGNC ID
HGNC:7
ORF Size (aa)
4425
ORF Size (bp)
4425 bp
RefSeq ID
NM_000014
RefSeq Synonyms
NM_001347425, NM_001347424, NM_001347423, NM_000014, BC040071,
Species
human
UniGene ID
Hs.212838
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.