rat CD44 shRNA silencing AAV

Name
AAV-r-CD44-shRNA

Cat No
shAAV-295083

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Cd44.

shAAV-295083

AAV-r-CD44-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Cd44 (CD44 molecule (Indian blood group)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CD44A; METAA; RHAMM

Description (Vector)

Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

Gene ID

25406

Gene Name (Vector)

CD44 molecule (Indian blood group)

Gene Symbol

Cd44

ORF Size (aa)

1095

ORF Size (bp)

1095 bp

RefSeq ID

NM_012924

RefSeq Synonyms

NM_012924, BC127485,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.