rat GZMB shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Gzmb.
shAAV-295082
AAV-r-GZMB-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Gzmb (granzyme B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RNKP-1
Description (Vector)
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Gene ID
171528
Gene Name (Vector)
granzyme B
Gene Symbol
Gzmb
ORF Size (aa)
741
RefSeq ID
NM_138517
RefSeq Synonyms
NM_138517, BC127475,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.