rat PCBP2 shRNA silencing AAV

Name
AAV-r-PCBP2-shRNA

Cat No
shAAV-294693

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Pcbp2.

shAAV-294693

AAV-r-PCBP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Pcbp2 (poly(rC) binding protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

100

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitinationa and degradation.

Gene ID

363005

Gene Name (Vector)

poly(rC) binding protein 2

Gene Symbol

Pcbp2

ORF Size (aa)

1008

RefSeq ID

NM_001013223

RefSeq Synonyms

NM_001013223, BC097410, BC078909, BC078906,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.