human ITGB8 Over-expression AAV

Name 
AAV-h-ITGB8
Cat No 
AAV-212518
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ITGB8.

AAV-212518
AAV-h-ITGB8

Ready-to-use AAV expressing Human ITGB8 (integrin subunit beta 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
ITGB8 is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Gene ID
3696
Gene Name (Vector)
integrin subunit beta 8
Gene Symbol
ITGB8
HGNC ID
HGNC:6163
ORF Size (aa)
1320
ORF Size (bp)
1320 bp
RefSeq ID
NM_002214
RefSeq Synonyms
NM_002214, BC002630,
Species
human
UniGene ID
Hs.592171

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.