human ITGA4 Over-expression AAV

Name 
AAV-h-ITGA4
Cat No 
AAV-212481
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ITGA4.

AAV-212481
AAV-h-ITGA4

Ready-to-use AAV expressing Human ITGA4 (integrin subunit alpha 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
269C wild type; alpha 4 subunit of VLA-4 receptor; antigen CD49D, alpha-4 subunit of VLA-4 receptor; CD antigen CD49d; CD49 antigen-like family member D; CD49D; IA4; integrin alpha-4; integrin alpha-IV; very late activation protein 4 receptor, alpha 4 subunit; VLA-4 subunit alpha
Description (eCommerce)
Integrin subunit alpha 4 (ITGA4) is a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling [taken from NCBI Entrez Gene (Gene ID: 3676)].
Description (Vector)
The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain.
Gene ID
3676
Gene Name (eCommerce)
integrin subunit alpha 4
Gene Name (Vector)
integrin subunit alpha 4
Gene Symbol
ITGA4
HGNC ID
HGNC:6140
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3099
ORF Size (bp)
3099 bp
Protein Name (eCommerce)
Integrin alpha-4
RefSeq ID
NM_000885
RefSeq Synonyms
NM_001316312, NM_000885, BC156712, BC146277, BC080190,
Research Areas
Cardiac Development,Cardiology,Cardiomyopathy,Cardiovascular,Cytoskeleton,Immunology,PI3K/Akt Signaling,Signal Transduction,VEGF Signaling
Research Areas (Faceted)
cardiovascular,cell_biology,developmental_biology,immunology,signal_transduction
Species
human
Target Sentence
Integrin subunit alpha 4 (ITGA4) is a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling [taken from NCBI Entrez Gene (Gene ID: 3676)].
UniGene ID
Hs.440955
UniProt ID (eCommerce)
P13612

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.