rat SREBF2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Srebf2.
shAAV-294206
AAV-r-SREBF2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Srebf2 (sterol regulatory element binding transcription factor 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Srebf2_retired; SREBP-2; SREBP2
Description (Vector)
Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway (By similarity). Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes.
Gene ID
300095
Gene Name (Vector)
sterol regulatory element binding transcription factor 2
Gene Symbol
Srebf2
ORF Size (aa)
3402
ORF Size (bp)
3402 bp
RefSeq ID
NM_001033694
RefSeq Synonyms
NM_001033694, BC101902,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.