rat NEDD8 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Nedd8.
shAAV-293887
AAV-r-NEDD8-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Nedd8 (neural precursor cell expressed, developmentally down-regulated 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CDK8
Description (Vector)
Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
Gene ID
25490
Gene Name (Vector)
neural precursor cell expressed, developmentally down-regulated 8
Gene Symbol
Nedd8
ORF Size (aa)
246
RefSeq ID
NM_138878
RefSeq Synonyms
NM_138878, BC084728,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.