rat ARL3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Arl3.
shAAV-293879
AAV-r-ARL3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Arl3 (ADP ribosylation factor like GTPase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase-activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins such as NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium. Does not act as an allosteric activator of the cholera toxin catalytic subunit.
Gene ID
64664
Gene Name (Vector)
ADP ribosylation factor like GTPase 3
Gene Symbol
Arl3
ORF Size (aa)
549
RefSeq ID
NM_022700
RefSeq Synonyms
NM_022700, BC084722,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.