rat ERRFI1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Errfi1.
shAAV-293604
AAV-r-ERRFI1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Errfi1 (ERBB receptor feedback inhibitor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
gene 33; Ralt; RGD1307599; Xxx
Description (Vector)
Negative regulator of EGFR signaling in skin morphogenesis. Acts as a negative regulator for several EGFR family members, including ERBB2, ERBB3 and ERBB4. Inhibits EGFR catalytic activity by interfering with its dimerization. Inhibits autophosphorylation of EGFR, ERBB2 and ERBB4. Important for normal keratinocyte proliferation and differentiation. Plays a role in modulating the response to steroid hormones in the uterus. Required for normal response to progesterone in the uterus and for fertility. Mediates epithelial estrogen responses in the uterus by regulating ESR1 levels and activation. Important for regulation of endometrium cell proliferation. Important for normal prenatal and perinatal lung development (By similarity).
Gene ID
313729
Gene Name (Vector)
ERBB receptor feedback inhibitor 1
Gene Symbol
Errfi1
ORF Size (aa)
1380
ORF Size (bp)
1380 bp
RefSeq ID
NM_001014071
RefSeq Synonyms
NM_001014071, BC083845,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.