rat DAPK2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Dapk2.
shAAV-293513
AAV-r-DAPK2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Dapk2 (death-associated protein kinase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation|Function: Isoform 2 can phosphorylate MYL9. It can induce membrane blebbing and autophagic cell death.
Gene ID
300799
Gene Name (Vector)
death-associated protein kinase 2
Gene Symbol
Dapk2
ORF Size (aa)
648
ORF Size (bp)
648 bp
RefSeq ID
NM_001013109
RefSeq Synonyms
NM_001013109, BC091410,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.