rat DNAJC7 shRNA silencing AAV

Name
AAV-r-DNAJC7-shRNA

Cat No
shAAV-293454

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Dnajc7.

shAAV-293454

AAV-r-DNAJC7-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Dnajc7 (DnaJ heat shock protein family (Hsp40) member C7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CCRP

Description (Vector)

Acts as co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. Recruits NR1I3 to the cytoplasm (By similarity).

Gene ID

303536

Gene Name (Vector)

DnaJ heat shock protein family (Hsp40) member C7

Gene Symbol

Dnajc7

ORF Size (aa)

1317

ORF Size (bp)

1317 bp

RefSeq ID

NM_213625

RefSeq Synonyms

NM_213625, BC093600,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.