rat RGD1307789 shRNA silencing AAV

Name
AAV-r-RGD1307789-shRNA

Cat No
shAAV-293154

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Mri1.

shAAV-293154

AAV-r-RGD1307789-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Mri1 (methylthioribose-1-phosphate isomerase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

RGD1307789

Description (Vector)

Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.

Gene ID

288912

Gene Name (Vector)

methylthioribose-1-phosphate isomerase 1

Gene Symbol

Mri1

ORF Size (aa)

1110

ORF Size (bp)

1110 bp

RefSeq ID

NM_001010947

RefSeq Synonyms

NM_001010947, BC089060,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.