rat MARCH2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat March2.
shAAV-292887
AAV-r-MARCH2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat March2 (membrane associated ring-CH-type finger 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MARCH-II; RGD1306395
Description (Vector)
E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May be involved in endosomal trafficking through interaction with STX6.
Gene ID
362849
Gene Name (Vector)
membrane associated ring-CH-type finger 2
Gene Symbol
2-Mar
ORF Size (aa)
741
ORF Size (bp)
741 bp
RefSeq ID
NM_001034108
RefSeq Synonyms
NM_001034108, BC088286,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.