rat NLRX1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Nlrx1.
shAAV-292824
AAV-r-NLRX1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Nlrx1 (NLR family member X1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RGD1311293
Description (Vector)
Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313).
Gene ID
315599
Gene Name (Vector)
NLR family member X1
Gene Symbol
Nlrx1
ORF Size (aa)
2922
ORF Size (bp)
2922 bp
RefSeq ID
NM_001025010
RefSeq Synonyms
NM_001025010, BC089834,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.