rat LPXN shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Lpxn.
shAAV-292765
AAV-r-LPXN-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Lpxn (leupaxin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin-induced tyrosine phosphorylation of paxillin (PXN). May play a critical role as an adapter protein in the formation of the adhesion zone in osteoclasts. Negatively regulates B-cell antigen receptor (BCR) signaling.
Gene ID
293783
Gene Name (Vector)
leupaxin
Gene Symbol
Lpxn
ORF Size (aa)
1161
RefSeq ID
NM_001009649
RefSeq Synonyms
NM_001009649, BC088217,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.