rat ARHGAP29 shRNA silencing AAV

Name
AAV-r-ARHGAP29-shRNA

Cat No
shAAV-292557

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Arhgap29.

shAAV-292557

AAV-r-ARHGAP29-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Arhgap29 (Rho GTPase activating protein 29). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

B130017i01rik; RGD1306185

Description (Vector)

GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho. In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis.

Gene ID

310833

Gene Name (Vector)

Rho GTPase activating protein 29

Gene Symbol

Arhgap29

ORF Size (aa)

3549

ORF Size (bp)

3549 bp

RefSeq ID

NM_001009405

RefSeq Synonyms

NM_001009405, BC087167,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.