rat KCNE3 shRNA silencing AAV

Name
AAV-r-KCNE3-shRNA

Cat No
shAAV-292212

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Kcne3.

shAAV-292212

AAV-r-KCNE3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Kcne3 (potassium voltage-gated channel subfamily E regulatory subunit 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Associated with KCNC4/Kv3.4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion.

Gene ID

63883

Gene Name (Vector)

potassium voltage-gated channel subfamily E regulatory subunit 3

Gene Symbol

Kcne3

ORF Size (aa)

324

ORF Size (bp)

324 bp

RefSeq ID

NM_022235

RefSeq Synonyms

NM_022235, BC086406,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.