rat GTF2I shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Gtf2i.
shAAV-292205
AAV-r-GTF2I-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Gtf2i (general transcription factor II I). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Gtf2ird1
Description (Vector)
Interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Promotes the formation of stable high-order complexes of SRF and PHOX1 and interacts cooperatively with PHOX1 to promote serum-inducible transcription of a reporter gene deriven by the C-FOS serum response element (SRE). Acts as a coregulator for USF1 by binding independently two promoter elements, a pyrimidine-rich initiator (Inr) and an upstream E-box. Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation.
Gene ID
353256
Gene Name (Vector)
general transcription factor II I
Gene Symbol
Gtf2i
ORF Size (aa)
2742
ORF Size (bp)
2742 bp
RefSeq ID
NM_001001512
RefSeq Synonyms
NM_001001512, BC085815,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.